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The potential dimer interface with the largest buried surface area was excluded from detailed analysis as the distance between the termini of each domain was too great to allow each domain to be linked by the interdomain linker peptide (86)

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Nrf2 degron-fused reporter system: a new tool for specific evaluation of Nrf2 inducers

phenytoin, griseofulvin, barbiturates, rifampin, thiazolidinediones) Concomitant use of amiodarone or verapamil causes an increased risk of myopathy Concomitant consumption of concentrated grapefruit juice, which destroys intestinal CYP 3A4 can cause ~12 fold increases in lovastatin plasma levels

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